ICD code definitions

CPT® Code 87807: Infectious Agent Antigen Detection, Respiratory Syncytial Virus (RSV)

May 29, 2026
3 min read
CPT® Code 87807: Infectious Agent Antigen Detection, Respiratory Syncytial Virus (RSV)

CPT® Code 87807 is used to report infectious agent antigen detection for respiratory syncytial virus (RSV) using an immunoassay technique (e.g., direct optical observation). This test provides rapid identification of RSV infection, supporting timely diagnosis and management, particularly in pediatric and high-risk populations.

This code typically reflects point-of-care or rapid testing, not molecular (PCR) methods, which are reported with different CPT codes.

Key Facts About CPT® 87807

  • Service type: Laboratory test (infectious disease, point-of-care)
  • Test: RSV antigen detection via immunoassay
  • Method: Immunoassay with direct optical observation
  • Specimen type: Nasal or nasopharyngeal swab
  • Test purpose: Rapid detection of RSV infection
  • Provider type: Physicians, laboratories, and qualified healthcare professionals

Common clinical indications:

  • Suspected RSV infection
  • Acute respiratory symptoms (e.g., cough, wheezing, fever)
  • Pediatric respiratory illness
  • Evaluation of infants, elderly, or immunocompromised patients
  • Seasonal respiratory infection screening

When to Use CPT® 87807

CPT 87807 is appropriate when:

  • Performing rapid RSV antigen detection using an immunoassay
  • Evaluating patients with acute respiratory symptoms
  • Immediate results are needed for clinical decision-making
  • The test is not performed using molecular (PCR) methods

Examples:

  • Testing an infant with bronchiolitis symptoms during RSV season
  • Rapid RSV screening in urgent care or pediatric clinic
  • Evaluating respiratory illness in high-risk populations
  • Differentiating RSV from other viral respiratory infections

Documentation Requirements

To support CPT 87807 billing, documentation should include:

  • Patient identifiers and date of service
  • Clinical indication for RSV testing
  • Specimen source (e.g., nasal swab)
  • Test performed (RSV antigen detection via immunoassay)
  • Test result and time performed
  • Ordering or supervising provider information

Clear documentation supports medical necessity and accurate billing for point-of-care testing.

Reimbursement and Coding Considerations

  • CPT 87807 is generally covered when medically necessary
  • Must reflect immunoassay methodology (not PCR or molecular testing)
  • May be subject to CLIA waiver requirements depending on the setting
  • Often used in outpatient, urgent care, and pediatric settings
  • Frequency and coverage may vary by payer

Always verify payer-specific infectious disease testing and CLIA requirements.

How OptiMantra Supports Respiratory Testing

OptiMantra’s integrated EMR and practice management platform streamlines documentation and billing for CPT 87807:

With OptiMantra, providers can:

  • Document point-of-care RSV testing directly within the patient chart
  • Capture real-time test results during patient visits
  • Link results to diagnoses and treatment plans
  • Maintain organized laboratory documentation that supports billing compliance and audit preparedness
  • Integrate respiratory testing workflows into a single system

By centralizing diagnostic workflows, OptiMantra helps practices improve efficiency, ensure compliance, and optimize reimbursement.

Try OptiMantra for free here!

Disclaimer: CPT® codes are maintained by the American Medical Association. This guide is for informational purposes only and does not replace official coding guidelines or payer policies.

Jessica Castro
Jessica Castro

Jessica is a Massachusetts-based LPN with 13+ years of experience in patient care, healthcare technology, and education. As the Implementation and Customer Success Manager at OptiMantra, she helps providers optimize EMR solutions for better workflows and patient outcomes. With a Bachelor's in Community Health and a Master's in Healthcare Innovation in progress, she is passionate about leveraging technology to improve care delivery. Through her writing, she shares insights on healthcare best practices, EHR optimization, and patient advocacy to support providers in delivering exceptional care.